Histone H3K27M Mutation Overrides Histological Grading in Pediatric Gliomas

Pediatric high-grade gliomas (HGG) are rare aggressive tumors that present a prognostic and therapeutic challenge. Diffuse midline glioma, H3K27M–mutant is a new entity introduced to HGG in the latest WHO classification. In this study we evaluated the presence of H3K27M mutation in 105 tumor samples...

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Udgivet i:Sci Rep
Main Authors: Mosaab, Amal, El-Ayadi, Moatasem, Khorshed, Eman N., Amer, Nada, Refaat, Amal, El-Beltagy, Mohamed, Hassan, Zeinab, Soror, Sameh H., Zaghloul, Mohamed Saad, El-Naggar, Shahenda
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7239884/
https://ncbi.nlm.nih.gov/pubmed/32433577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65272-x
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