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Loss of Ena/VASP interferes with lamellipodium architecture, motility and integrin-dependent adhesion
Cell migration entails networks and bundles of actin filaments termed lamellipodia and microspikes or filopodia, respectively, as well as focal adhesions, all of which recruit Ena/VASP family members hitherto thought to antagonize efficient cell motility. However, we find these proteins to act as po...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7239657/ https://ncbi.nlm.nih.gov/pubmed/32391788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.55351 |
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