Molecular mechanism of Ena/VASP-mediated actin-filament elongation

Ena/VASP proteins are implicated in a variety of fundamental cellular processes including axon guidance and cell migration. In vitro, they enhance elongation of actin filaments, but at rates differing in nearly an order of magnitude according to species, raising questions about the molecular determi...

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Main Authors: Breitsprecher, Dennis, Kiesewetter, Antje K, Linkner, Joern, Vinzenz, Marlene, Stradal, Theresia E B, Small, John Victor, Curth, Ute, Dickinson, Richard B, Faix, Jan
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3034019/
https://ncbi.nlm.nih.gov/pubmed/21217643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.348
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