Ena/VASP processive elongation is modulated by avidity on actin filaments bundled by the filopodia cross-linker fascin

Ena/VASP tetramers are processive actin elongation factors that localize to diverse F-actin networks composed of filaments bundled by different cross-linking proteins, such as filopodia (fascin), lamellipodia (fimbrin), and stress fibers (α-actinin). Previously, we found that Ena takes approximately...

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Udgivet i:Mol Biol Cell
Main Authors: Harker, Alyssa J., Katkar, Harshwardhan H., Bidone, Tamara C., Aydin, Fikret, Voth, Gregory A., Applewhite, Derek A., Kovar, David R.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2019
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6589784/
https://ncbi.nlm.nih.gov/pubmed/30601697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-08-0500
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