Clustering of VASP actively drives processive, WH2 domain-mediated actin filament elongation

Vasodilator-stimulated phosphoprotein (VASP) is a key regulator of dynamic actin structures like filopodia and lamellipodia, but its precise function in their formation is controversial. Using in vitro TIRF microscopy, we show for the first time that both human and Dictyostelium VASP are directly in...

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Detalhes bibliográficos
Main Authors: Breitsprecher, Dennis, Kiesewetter, Antje K, Linkner, Joern, Urbanke, Claus, Resch, Guenter P, Small, J Victor, Faix, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2585163/
https://ncbi.nlm.nih.gov/pubmed/18923426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.211
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