CDC42 switches IRSp53 from inhibition of actin growth to elongation by clustering of VASP

Filopodia explore the environment, sensing soluble and mechanical cues during directional motility and tissue morphogenesis. How filopodia are initiated and spatially restricted to specific sites on the plasma membrane is still unclear. Here, we show that the membrane deforming and curvature sensing...

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Autori principali: Disanza, Andrea, Bisi, Sara, Winterhoff, Moritz, Milanesi, Francesca, Ushakov, Dmitry S, Kast, David, Marighetti, Paola, Romet-Lemonne, Guillaume, Müller, Hans-Michael, Nickel, Walter, Linkner, Joern, Waterschoot, Davy, Ampè, Christophe, Cortellino, Salvatore, Palamidessi, Andrea, Dominguez, Roberto, Carlier, Marie-France, Faix, Jan, Scita, Giorgio
Natura: Artigo
Lingua:Inglês
Pubblicazione: European Molecular Biology Organization 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3801440/
https://ncbi.nlm.nih.gov/pubmed/24076653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.208
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