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The sequence of human ACE2 is suboptimal for binding the S spike protein of SARS coronavirus 2
The rapid and escalating spread of SARS coronavirus 2 (SARS-CoV-2) poses an immediate public health emergency. The viral spike protein S binds ACE2 on host cells to initiate molecular events that release the viral genome intracellularly. Soluble ACE2 inhibits entry of both SARS and SARS-2 coronaviru...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | bioRxiv |
|---|---|
| Prif Awdur: | |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Cold Spring Harbor Laboratory
2020
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7239051/ https://ncbi.nlm.nih.gov/pubmed/32511321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.03.16.994236 |
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