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The sequence of human ACE2 is suboptimal for binding the S spike protein of SARS coronavirus 2
The rapid and escalating spread of SARS coronavirus 2 (SARS-CoV-2) poses an immediate public health emergency. The viral spike protein S binds ACE2 on host cells to initiate molecular events that release the viral genome intracellularly. Soluble ACE2 inhibits entry of both SARS and SARS-2 coronaviru...
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| Publicado no: | bioRxiv |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7239051/ https://ncbi.nlm.nih.gov/pubmed/32511321 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2020.03.16.994236 |
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