White matter hyperintensities and CSF Alzheimer disease biomarkers in preclinical Alzheimer disease

OBJECTIVE: Recent studies suggest that white matter hyperintensities (WMH) on MRI, which primarily reflect small vessel cerebrovascular disease, may play a role in the evolution of Alzheimer disease (AD). In a longitudinal study, we investigated whether WMH promote the progression of AD pathology, o...

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Publicado en:Neurology
Autores principales: Soldan, Anja, Pettigrew, Corinne, Zhu, Yuxin, Wang, Mei-Cheng, Moghekar, Abhay, Gottesman, Rebecca F., Singh, Baljeet, Martinez, Oliver, Fletcher, Evan, DeCarli, Charles, Albert, Marilyn
Formato: Artigo
Lenguaje:Inglês
Publicado: Lippincott Williams & Wilkins 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238945/
https://ncbi.nlm.nih.gov/pubmed/31888969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000008864
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