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Relationship of cognitive reserve and CSF biomarkers to emergence of clinical symptoms in preclinical Alzheimer’s Disease

Levels of β-amyloid and phosphorylated tau (p-tau), as measured in cerebrospinal fluid (CSF), have been associated with risk of progressing from normal cognition to onset of clinical symptoms during preclinical Alzheimer’s disease (AD). We examined whether cognitive reserve (CR) modifies this associ...

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Detalhes bibliográficos
Main Authors: Soldan, Anja, Pettigrew, Corinne, Li, Shanshan, Wang, Mei-Cheng, Moghekar, Abhay, Selnes, Ola A., Albert, Marilyn, O’Brien, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823238/
https://ncbi.nlm.nih.gov/pubmed/23916061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2013.06.017
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