Relationship of cognitive reserve and CSF biomarkers to emergence of clinical symptoms in preclinical Alzheimer’s Disease

Levels of β-amyloid and phosphorylated tau (p-tau), as measured in cerebrospinal fluid (CSF), have been associated with risk of progressing from normal cognition to onset of clinical symptoms during preclinical Alzheimer’s disease (AD). We examined whether cognitive reserve (CR) modifies this associ...

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Détails bibliographiques
Auteurs principaux: Soldan, Anja, Pettigrew, Corinne, Li, Shanshan, Wang, Mei-Cheng, Moghekar, Abhay, Selnes, Ola A., Albert, Marilyn, O’Brien, Richard
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823238/
https://ncbi.nlm.nih.gov/pubmed/23916061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2013.06.017
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