Relationship of Cognitive Reserve and APOE Status to the Emergence of Clinical Symptoms in Preclinical Alzheimer’s Disease

The APOE ε4 allele increases the risk of developing Alzheimer’s disease, whereas the APOE ε2 allele reduces risk. We examined whether cognitive reserve (CR), as measured by an index consisting of education, reading, and vocabulary, modifies these associations. CR was measured at baseline in 257 cogn...

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Main Authors: Pettigrew, Corinne, Soldan, Anja, Li, Shanshan, Lu, Yi, Wang, Mei-Cheng, Selnes, Ola A., Moghekar, Abhay, O’Brien, Richard, Albert, Marilyn
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836845/
https://ncbi.nlm.nih.gov/pubmed/24168200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17588928.2013.831820
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