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Identifying Changepoints in Biomarkers During the Preclinical Phase of Alzheimer’s Disease

Objective: Several models have been proposed for the evolution of Alzheimer’s disease (AD) biomarkers. The aim of this study was to identify changepoints in a range of biomarkers during the preclinical phase of AD. Methods: We examined nine measures based on cerebrospinal fluid (CSF), magnetic reson...

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Pubblicato in:Front Aging Neurosci
Autori principali: Younes, Laurent, Albert, Marilyn, Moghekar, Abhay, Soldan, Anja, Pettigrew, Corinne, Miller, Michael I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454004/
https://ncbi.nlm.nih.gov/pubmed/31001108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2019.00074
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