MR biomarkers predict clinical function in Duchenne muscular dystrophy

OBJECTIVE: To investigate the potential of lower extremity magnetic resonance (MR) biomarkers to serve as endpoints in clinical trials of therapeutics for Duchenne muscular dystrophy (DMD) by characterizing the longitudinal progression of MR biomarkers over 48 months and assessing their relationship...

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Pubblicato in:Neurology
Autori principali: Barnard, Alison M., Willcocks, Rebecca J., Triplett, William T., Forbes, Sean C., Daniels, Michael J., Chakraborty, Saptarshi, Lott, Donovan J., Senesac, Claudia R., Finanger, Erika L., Harrington, Ann T., Tennekoon, Gihan, Arora, Harneet, Wang, Dah-Jyuu, Sweeney, H. Lee, Rooney, William D., Walter, Glenn A., Vandenborne, Krista
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7238941/
https://ncbi.nlm.nih.gov/pubmed/32024675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000009012
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