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Loss of epigenetic modifications on the inactive X chromosome and sex-biased gene expression profiles in B cells from NZB/W F1 mice with lupus-like disease
The mechanisms underlying the female-bias in autoimmunity are poorly understood. The contribution of genetic and epigenetics factors from the inactive X chromosome (Xi) are beginning to emerge as critical mediators of autoimmunity in females. Here, we ask how epigenetic features of the Xi change dur...
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| Опубликовано в: : | J Autoimmun |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7237307/ https://ncbi.nlm.nih.gov/pubmed/31780316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2019.102357 |
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