Ovarian primary and metastatic tumors suppressed by survivin knockout or a novel survivin inhibitor

Survivin, a member of the inhibitor of apoptosis (IAP) family, is upregulated in multiple cancers including ovarian cancer, but is rarely detectable in normal tissues. We previously reported that survivin promoted epithelial to mesenchymal transition (EMT) in ovarian cancer cells, suggesting that su...

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Vydáno v:Mol Cancer Ther
Hlavní autoři: Zhao, Guannan, Wang, Qinghui, Wu, Zhongzhi, Tian, Xinchun, Yan, Huan, Wang, Baojin, Dong, Peixin, Watari, Hidemichi, Pfeffer, Lawrence M., Guo, Yuqi, Li, Wei, Yue, Junming
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7236622/
https://ncbi.nlm.nih.gov/pubmed/31515295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-19-0118
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