Ovarian primary and metastatic tumors suppressed by survivin knockout or a novel survivin inhibitor

Survivin, a member of the inhibitor of apoptosis (IAP) family, is upregulated in multiple cancers including ovarian cancer, but is rarely detectable in normal tissues. We previously reported that survivin promoted epithelial to mesenchymal transition (EMT) in ovarian cancer cells, suggesting that su...

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Bibliografske podrobnosti
izdano v:Mol Cancer Ther
Main Authors: Zhao, Guannan, Wang, Qinghui, Wu, Zhongzhi, Tian, Xinchun, Yan, Huan, Wang, Baojin, Dong, Peixin, Watari, Hidemichi, Pfeffer, Lawrence M., Guo, Yuqi, Li, Wei, Yue, Junming
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7236622/
https://ncbi.nlm.nih.gov/pubmed/31515295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-19-0118
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