Ovarian primary and metastatic tumors suppressed by survivin knockout or a novel survivin inhibitor

Survivin, a member of the inhibitor of apoptosis (IAP) family, is upregulated in multiple cancers including ovarian cancer, but is rarely detectable in normal tissues. We previously reported that survivin promoted epithelial to mesenchymal transition (EMT) in ovarian cancer cells, suggesting that su...

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Publicado en:Mol Cancer Ther
Autores principales: Zhao, Guannan, Wang, Qinghui, Wu, Zhongzhi, Tian, Xinchun, Yan, Huan, Wang, Baojin, Dong, Peixin, Watari, Hidemichi, Pfeffer, Lawrence M., Guo, Yuqi, Li, Wei, Yue, Junming
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7236622/
https://ncbi.nlm.nih.gov/pubmed/31515295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-19-0118
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