Circ-OXCT1 Suppresses Gastric Cancer EMT and Metastasis by Attenuating TGF-β Pathway Through the Circ-OXCT1/miR-136/SMAD4 Axis

BACKGROUND: Circular RNAs (circRNAs) have been proven to play important roles in tumorigenesis. However, the mechanism by which circRNAs act on gastric cancer (GC) through epithelial-to-mesenchymal transition (EMT) is unclear. In this study, we identified circ-OXCT1 and elucidated its function on EM...

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Veröffentlicht in:Onco Targets Ther
Hauptverfasser: Liu, Jianjun, Dai, Xinglong, Guo, Xiong, Cheng, Anqi, Mac, Sandrie Mariella, Wang, Ziwei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2020
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7236241/
https://ncbi.nlm.nih.gov/pubmed/32523351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S239789
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