SALL4 activates TGF-β/SMAD signaling pathway to induce EMT and promote gastric cancer metastasis

BACKGROUND: Increasing evidence suggests that SALL4 plays oncogenic roles in cancer development and progression. We have previously shown that SALL4 is highly expressed in gastric cancer, and its upregulation is associated with lymph node metastasis and poor prognosis. The role of SALL4 in gastric c...

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Foilsithe in:Cancer Manag Res
Main Authors: Zhang, Xu, Zhang, Peng, Shao, Meng, Zang, Xueyan, Zhang, Jiayin, Mao, Fei, Qian, Hui, Xu, Wenrong
Formáid: Artigo
Teanga:Inglês
Foilsithe: Dove Medical Press 2018
Ábhair:
Original Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6188178/
https://ncbi.nlm.nih.gov/pubmed/30349378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CMAR.S177373
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