Discovery and development of small-molecule inhibitors of glycogen synthase

The over-accumulation of glycogen appears as a hallmark in various glycogen storage diseases (GSDs), including Pompe, Cori, Andersen and Lafora disease. Accumulating evidence suggests that suppression of glycogen accumulation represents a potential therapeutic approach for treating these GSDs. Using...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Tang, Buyun, Frasinyuk, Mykhaylo S., Chikwana, Vimbai M., Mahalingan, Krishna K., Morgan, Cynthia A., Segvich, Dyann M., Bondarenko, Svitlana P., Mrug, Galyna P., Wyrebek, Przemyslaw, Watt, David S., DePaoli-Roach, Anna A., Roach, Peter J., Hurley, Thomas D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7233370/
https://ncbi.nlm.nih.gov/pubmed/32134266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.9b01851
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados