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Structural basis for 2′-phosphate incorporation into glycogen by glycogen synthase

Glycogen is a glucose polymer that contains minor amounts of covalently attached phosphate. Hyperphosphorylation is deleterious to glycogen structure and can lead to Lafora disease. Recently, it was demonstrated that glycogen synthase catalyzes glucose–phosphate transfer in addition to its character...

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Autores principales: Chikwana, Vimbai M., Khanna, May, Baskaran, Sulochanadevi, Tagliabracci, Vincent S., Contreras, Christopher J., DePaoli-Roach, Anna, Roach, Peter J., Hurley, Thomas D.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876246/
https://ncbi.nlm.nih.gov/pubmed/24324135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310106111
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