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Structural basis for 2′-phosphate incorporation into glycogen by glycogen synthase

Glycogen is a glucose polymer that contains minor amounts of covalently attached phosphate. Hyperphosphorylation is deleterious to glycogen structure and can lead to Lafora disease. Recently, it was demonstrated that glycogen synthase catalyzes glucose–phosphate transfer in addition to its character...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chikwana, Vimbai M., Khanna, May, Baskaran, Sulochanadevi, Tagliabracci, Vincent S., Contreras, Christopher J., DePaoli-Roach, Anna, Roach, Peter J., Hurley, Thomas D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3876246/
https://ncbi.nlm.nih.gov/pubmed/24324135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310106111
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