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Redox switch for the inhibited state of yeast glycogen synthase mimics regulation by phosphorylation
Glycogen synthase (GS) is the rate limiting enzyme in the synthesis of glycogen. Eukaryotic GS is negatively regulated by covalent phosphorylation and allosterically activated by glucose-6-phosphate (G6P). To gain structural insights into the inhibited state of the enzyme, we solved the crystal stru...
Gorde:
| Argitaratua izan da: | Biochemistry |
|---|---|
| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2016
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5516924/ https://ncbi.nlm.nih.gov/pubmed/27935293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00884 |
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