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Cancer Cells Upregulate NRF2 Signaling to Adapt to Autophagy Inhibition
While autophagy is thought to be an essential process in some cancer cells, it is unknown if or how such cancer cells can circumvent autophagy inhibition. To address this, we developed a CRISPR/ Cas9 assay with dynamic live-cell imaging to measure acute effects of knockout (KO) of autophagy genes co...
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| Publicado no: | Dev Cell |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7233142/ https://ncbi.nlm.nih.gov/pubmed/31378590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.07.010 |
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