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RNA-Binding Domains of Heterologous Viral Proteins Substituted for Basic Residues in the RSV Gag NC Domain Restore Specific Packaging of Genomic RNA

The Rous sarcoma virus Gag polyprotein transiently traffics through the nucleus, which is required for efficient incorporation of the viral genomic RNA (gRNA) into virus particles. Packaging of gRNA is mediated by two zinc knuckles and basic residues located in the nucleocapsid (NC) domain in Gag. T...

詳細記述

保存先:
書誌詳細
出版年:Viruses
主要な著者: Rice, Breanna L., Lochmann, Timothy L., Parent, Leslie J.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232437/
https://ncbi.nlm.nih.gov/pubmed/32230826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12040370
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