Alterations in the MA and NC Domains Modulate Phosphoinositide-Dependent Plasma Membrane Localization of the Rous Sarcoma Virus Gag Protein

Retroviral Gag proteins direct virus particle assembly from the plasma membrane (PM). Phosphatidylinositol-(4,5)-bisphosphate [PI(4,5)P(2)] plays a role in PM targeting of several retroviral Gag proteins. Here we report that depletion of intracellular PI(4,5)P(2) and phosphatidylinositol-(3,4,5)-tri...

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Detalhes bibliográficos
Main Authors: Nadaraia-Hoke, Shorena, Bann, Darrin V., Lochmann, Timothy L., Gudleski-O'Regan, Nicole, Parent, Leslie J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3592118/
https://ncbi.nlm.nih.gov/pubmed/23325682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03059-12
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