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Insertion of a Classical Nuclear Import Signal into the Matrix Domain of the Rous Sarcoma Virus Gag Protein Interferes with Virus Replication

The Rous sarcoma virus Gag protein undergoes transient nuclear trafficking during virus assembly. Nuclear import is mediated by a nuclear targeting sequence within the MA domain. To gain insight into the role of nuclear transport in replication, we investigated whether addition of a “classical ” nuc...

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Bibliografiske detaljer
Main Authors: Garbitt, Rachel A., Bone, Karen R., Parent, Leslie J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC533892/
https://ncbi.nlm.nih.gov/pubmed/15564464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.24.13534-13542.2004
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