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trans-Acting Inhibition of Genomic RNA Dimerization by Rous Sarcoma Virus Matrix Mutants

The genomic RNA of retroviruses exists within the virion as a noncovalently linked dimer. Previously, we identified a mutant of the viral matrix (MA) protein of Rous sarcoma virus that disrupts viral RNA dimerization. This mutant, Myr1E, is modified at the N terminus of MA by the addition of 10 amin...

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Detalhes bibliográficos
Main Authors: Garbitt, Rachel A., Albert, Jessica A., Kessler, Michelle D., Parent, Leslie J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC113920/
https://ncbi.nlm.nih.gov/pubmed/11119596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.1.260-268.2001
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