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A Heterologous, High-Affinity RNA Ligand for Human Immunodeficiency Virus Gag Protein Has RNA Packaging Activity

Retroviral RNA encapsidation depends on the specific binding of Gag proteins to packaging (ψ) signals in genomic RNA. We investigated whether an in vitro-selected, high-affinity RNA ligand for the nucleocapsid (NC) portion of the Gag protein from human immunodeficiency virus type 1 (HIV-1) could med...

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Detalhes bibliográficos
Main Authors: Clever, Jared L., Taplitz, Randy A., Lochrie, Michael A., Polisky, Barry, Parslow, Tristram G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC111568/
https://ncbi.nlm.nih.gov/pubmed/10590146
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