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A Heterologous, High-Affinity RNA Ligand for Human Immunodeficiency Virus Gag Protein Has RNA Packaging Activity

Retroviral RNA encapsidation depends on the specific binding of Gag proteins to packaging (ψ) signals in genomic RNA. We investigated whether an in vitro-selected, high-affinity RNA ligand for the nucleocapsid (NC) portion of the Gag protein from human immunodeficiency virus type 1 (HIV-1) could med...

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書誌詳細
主要な著者: Clever, Jared L., Taplitz, Randy A., Lochrie, Michael A., Polisky, Barry, Parslow, Tristram G.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2000
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC111568/
https://ncbi.nlm.nih.gov/pubmed/10590146
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