A Heterologous, High-Affinity RNA Ligand for Human Immunodeficiency Virus Gag Protein Has RNA Packaging Activity

Retroviral RNA encapsidation depends on the specific binding of Gag proteins to packaging (ψ) signals in genomic RNA. We investigated whether an in vitro-selected, high-affinity RNA ligand for the nucleocapsid (NC) portion of the Gag protein from human immunodeficiency virus type 1 (HIV-1) could med...

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Pubblicato in:	J Virol
Autori principali:	Clever, Jared L., Taplitz, Randy A., Lochrie, Michael A., Polisky, Barry, Parslow, Tristram G.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Structure and Assembly
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111568/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10590146/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.1.541-546.2000
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