Development of a non-alcoholic steatohepatitis model with rapid accumulation of fibrosis, and its treatment using mesenchymal stem cells and their small extracellular vesicles

INTRODUCTION: Currently, there are no approved drugs for treating non-alcoholic steatohepatitis (NASH); however, mesenchymal stem cells (MSCs) and their small extracellular vesicles (sEVs), which possess immunomodulatory activities, are potential candidates. This study aimed to develop a mouse model...

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Pubblicato in:Regen Ther
Autori principali: Watanabe, Takayuki, Tsuchiya, Atsunori, Takeuchi, Suguru, Nojiri, Shunsuke, Yoshida, Tomoaki, Ogawa, Masahiro, Itoh, Michiko, Takamura, Masaaki, Suganami, Takayoshi, Ogawa, Yoshihiro, Terai, Shuji
Natura: Artigo
Lingua:Inglês
Pubblicazione: Japanese Society for Regenerative Medicine 2020
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232114/
https://ncbi.nlm.nih.gov/pubmed/32455155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.reth.2020.03.012
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