Small extracellular vesicles derived from interferon-γ pre-conditioned mesenchymal stromal cells effectively treat liver fibrosis

Mesenchymal stromal cells (MSCs) are used for ameliorating liver fibrosis and aiding liver regeneration after cirrhosis; Here, we analyzed the therapeutic potential of small extracellular vesicles (sEVs) derived from interferon-γ (IFN-γ) pre-conditioned MSCs (γ-sEVs). γ-sEVs effectively induced anti...

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Publicado no:NPJ Regen Med
Main Authors: Takeuchi, Suguru, Tsuchiya, Atsunori, Iwasawa, Takahiro, Nojiri, Shunsuke, Watanabe, Takayuki, Ogawa, Masahiro, Yoshida, Tomoaki, Fujiki, Katsunori, Koui, Yuta, Kido, Taketomo, Yoshioka, Yusuke, Fujita, Mayu, Kikuta, Junichi, Itoh, Tohru, Takamura, Masaaki, Shirahige, Katsuhiko, Ishii, Masaru, Ochiya, Takahiro, Miyajima, Atsushi, Terai, Shuji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8010072/
https://ncbi.nlm.nih.gov/pubmed/33785758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41536-021-00132-4
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