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In case of stress, hold tight: phosphorylation switches PDI from an oxidoreductase to a holdase, tuning ER proteostasis
Eukaryotic cells have evolved multiple responses that allow endoplasmic reticulum (ER) homeostasis to be maintained even in the face of acute or chronic stresses. In this issue, Yu et al (2020) describe how site‐specific phosphorylation switches protein disulfide isomerase (PDI) from a folding enzym...
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| Publicado no: | EMBO J |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7231998/ https://ncbi.nlm.nih.gov/pubmed/32239769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020104880 |
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