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The Selectivity Filter Is Involved in the U-Type Inactivation Process of Kv2.1 and Kv3.1 Channels

Voltage-gated potassium (Kv) channels display several types of inactivation processes, including N-, C-, and U-types. C-type inactivation is attributed to a nonconductive conformation of the selectivity filter (SF). It has been proposed that the activation gate and the channel’s SF are allostericall...

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Dettagli Bibliografici
Pubblicato in:Biophys J
Autori principali: Coonen, Laura, Mayeur, Evy, De Neuter, Nicolas, Snyders, Dirk J., Cuello, Luis G., Labro, Alain J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7231921/
https://ncbi.nlm.nih.gov/pubmed/32365329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.03.032
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