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Resistance Mechanisms towards CD38−Directed Antibody Therapy in Multiple Myeloma
Antibodies targeting CD38 are rapidly changing the treatment landscape of multiple myeloma (MM). CD38−directed antibodies have several mechanisms of action. Fc−dependent immune effector mechanisms include complement-dependent cytotoxicity (CDC), antibody−dependent cell−mediated cytotoxicity (ADCC),...
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| Publicado no: | J Clin Med |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7230744/ https://ncbi.nlm.nih.gov/pubmed/32331242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9041195 |
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