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CD38 Antibodies in Multiple Myeloma: Mechanisms of Action and Modes of Resistance

MM cells express high levels of CD38, while CD38 is expressed at relatively low levels on normal lymphoid and myeloid cells, and in some non-hematopoietic tissues. This expression profile, together with the role of CD38 in adhesion and as ectoenzyme, resulted in the development of CD38 antibodies fo...

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Dades bibliogràfiques
Publicat a:Front Immunol
Autors principals: van de Donk, Niels W.C.J., Usmani, Saad Z.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158369/
https://ncbi.nlm.nih.gov/pubmed/30294326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02134
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