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CD38 Antibodies in Multiple Myeloma: Mechanisms of Action and Modes of Resistance

MM cells express high levels of CD38, while CD38 is expressed at relatively low levels on normal lymphoid and myeloid cells, and in some non-hematopoietic tissues. This expression profile, together with the role of CD38 in adhesion and as ectoenzyme, resulted in the development of CD38 antibodies fo...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: van de Donk, Niels W.C.J., Usmani, Saad Z.
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6158369/
https://ncbi.nlm.nih.gov/pubmed/30294326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02134
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