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CD38-targeted therapy with daratumumab reduces autoantibody levels in multiple myeloma patients
Autoantibody-producing plasma cells are frequently resistant to conventional immunosuppressive treatments and B-cell depletion therapy. As a result of this resistance, autoreactive plasma cells survive conventional therapy, resulting in persistent autoantibody production and inflammation. CD38 is hi...
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| Publicado no: | J Transl Autoimmun |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7388400/ https://ncbi.nlm.nih.gov/pubmed/32743508 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtauto.2019.100022 |
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