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Lipidomics-based assays coupled with computational approaches can identify novel phospholipase A(2) inhibitors

Phospholipase A(2) (PLA(2)) enzymes play a major role in many diseases including the inflammatory cascade and specific potent small molecule inhibitors could be useful in studying their physiological role as well as for the development of drugs. In order to discover novel small molecule inhibitor pl...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Adv Biol Regul
Main Authors: Mouchlis, Varnavas D., Mu, Carol, Hammons, Renee, Dennis, Edward A.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7230010/
https://ncbi.nlm.nih.gov/pubmed/32199750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbior.2020.100719
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