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Lipidomics-based assays coupled with computational approaches can identify novel phospholipase A(2) inhibitors

Phospholipase A(2) (PLA(2)) enzymes play a major role in many diseases including the inflammatory cascade and specific potent small molecule inhibitors could be useful in studying their physiological role as well as for the development of drugs. In order to discover novel small molecule inhibitor pl...

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Detalhes bibliográficos
Publicado no:Adv Biol Regul
Main Authors: Mouchlis, Varnavas D., Mu, Carol, Hammons, Renee, Dennis, Edward A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7230010/
https://ncbi.nlm.nih.gov/pubmed/32199750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbior.2020.100719
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