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Lipidomics-based assays coupled with computational approaches can identify novel phospholipase A(2) inhibitors

Phospholipase A(2) (PLA(2)) enzymes play a major role in many diseases including the inflammatory cascade and specific potent small molecule inhibitors could be useful in studying their physiological role as well as for the development of drugs. In order to discover novel small molecule inhibitor pl...

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Bibliografiske detaljer
Udgivet i:Adv Biol Regul
Main Authors: Mouchlis, Varnavas D., Mu, Carol, Hammons, Renee, Dennis, Edward A.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7230010/
https://ncbi.nlm.nih.gov/pubmed/32199750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbior.2020.100719
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