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Lipidomics-based assays coupled with computational approaches can identify novel phospholipase A(2) inhibitors

Phospholipase A(2) (PLA(2)) enzymes play a major role in many diseases including the inflammatory cascade and specific potent small molecule inhibitors could be useful in studying their physiological role as well as for the development of drugs. In order to discover novel small molecule inhibitor pl...

詳細記述

保存先:
書誌詳細
出版年:Adv Biol Regul
主要な著者: Mouchlis, Varnavas D., Mu, Carol, Hammons, Renee, Dennis, Edward A.
フォーマット: Artigo
言語:Inglês
出版事項: 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7230010/
https://ncbi.nlm.nih.gov/pubmed/32199750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbior.2020.100719
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