PAM recognition by miniature CRISPR–Cas12f nucleases triggers programmable double-stranded DNA target cleavage

In recent years, CRISPR-associated (Cas) nucleases have revolutionized the genome editing field. Being guided by an RNA to cleave double-stranded (ds) DNA targets near a short sequence termed a protospacer adjacent motif (PAM), Cas9 and Cas12 offer unprecedented flexibility, however, more compact ve...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Karvelis, Tautvydas, Bigelyte, Greta, Young, Joshua K, Hou, Zhenglin, Zedaveinyte, Rimante, Budre, Karolina, Paulraj, Sushmitha, Djukanovic, Vesna, Gasior, Stephen, Silanskas, Arunas, Venclovas, Česlovas, Siksnys, Virginijus
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Nucleic Acid Enzymes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229846/
https://ncbi.nlm.nih.gov/pubmed/32246713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa208
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados