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DnaQ exonuclease‐like domain of Cas2 promotes spacer integration in a type I‐E CRISPR‐Cas system

CRISPR‐Cas systems constitute an adaptive immune system that provides acquired resistance against phages and plasmids in prokaryotes. Upon invasion of foreign nucleic acids, some cells integrate short fragments of foreign DNA as spacers into the CRISPR locus to memorize the invaders and acquire resi...

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Bibliografske podrobnosti
izdano v:EMBO Rep
Main Authors: Drabavicius, Gediminas, Sinkunas, Tomas, Silanskas, Arunas, Gasiunas, Giedrius, Venclovas, Česlovas, Siksnys, Virginijus
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6030702/
https://ncbi.nlm.nih.gov/pubmed/29891635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201745543
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