Molecular basis of the multifaceted functions of human leucyl-tRNA synthetase in protein synthesis and beyond

Human cytosolic leucyl-tRNA synthetase (hcLRS) is an essential and multifunctional enzyme. Its canonical function is to catalyze the covalent ligation of leucine to tRNA(Leu), and it may also hydrolyze mischarged tRNAs through an editing mechanism. Together with eight other aminoacyl-tRNA synthetase...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Liu, Ru-Juan, Long, Tao, Li, Hao, Zhao, JingHua, Li, Jing, Wang, MingZhu, Palencia, Andrés, Lin, JinZhong, Cusack, Stephen, Wang, En-Duo
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Molecular Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229842/
https://ncbi.nlm.nih.gov/pubmed/32232361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa189
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