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Molecular basis of the multifaceted functions of human leucyl-tRNA synthetase in protein synthesis and beyond

Human cytosolic leucyl-tRNA synthetase (hcLRS) is an essential and multifunctional enzyme. Its canonical function is to catalyze the covalent ligation of leucine to tRNA(Leu), and it may also hydrolyze mischarged tRNAs through an editing mechanism. Together with eight other aminoacyl-tRNA synthetase...

詳細記述

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書誌詳細
出版年:Nucleic Acids Res
主要な著者: Liu, Ru-Juan, Long, Tao, Li, Hao, Zhao, JingHua, Li, Jing, Wang, MingZhu, Palencia, Andrés, Lin, JinZhong, Cusack, Stephen, Wang, En-Duo
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229842/
https://ncbi.nlm.nih.gov/pubmed/32232361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa189
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