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Fibroblast rejuvenation by mechanical reprogramming and redifferentiation
Over the course of the aging process, fibroblasts lose contractility, leading to reduced connective-tissue stiffness. A promising therapeutic avenue for functional rejuvenation of connective tissue is reprogrammed fibroblast replacement, although major hurdles still remain. Toward this, we recently...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7229653/ https://ncbi.nlm.nih.gov/pubmed/32350144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1911497117 |
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