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Fibroblast rejuvenation by mechanical reprogramming and redifferentiation
Over the course of the aging process, fibroblasts lose contractility, leading to reduced connective-tissue stiffness. A promising therapeutic avenue for functional rejuvenation of connective tissue is reprogrammed fibroblast replacement, although major hurdles still remain. Toward this, we recently...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7229653/ https://ncbi.nlm.nih.gov/pubmed/32350144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1911497117 |
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