Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype

Multiple sclerosis (MS) is a chronic disease that is characterized by demyelination and axonal damage in the central nervous system. Cognitive deficits are recognized as one of the features of MS, and these deficits affect the patients’ quality of life. Increasing evidence from experimental autoimmu...

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Опубликовано в: :Cell Death Dis
Главные авторы: Hou, Baohua, Zhang, Yahui, Liang, Peiyu, He, Yuan, Peng, Biwen, Liu, Wanhong, Han, Song, Yin, Jun, He, Xiaohua
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229224/
https://ncbi.nlm.nih.gov/pubmed/32415059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2565-2
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