Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease

Cell replacement is a long-standing and realistic goal for the treatment of Parkinsonʼs disease (PD). Cells for transplantation can be obtained from fetal brain tissue or from stem cells. However, after transplantation, dopamine (DA) neurons are seen to be a minor component of grafts, and it has rem...

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Publicado no:Nat Commun
Main Authors: Tiklová, Katarína, Nolbrant, Sara, Fiorenzano, Alessandro, Björklund, Åsa K., Sharma, Yogita, Heuer, Andreas, Gillberg, Linda, Hoban, Deirdre B., Cardoso, Tiago, Adler, Andrew F., Birtele, Marcella, Lundén-Miguel, Hilda, Volakakis, Nikolaos, Kirkeby, Agnete, Perlmann, Thomas, Parmar, Malin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7229159/
https://ncbi.nlm.nih.gov/pubmed/32415072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16225-5
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