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A role for actin flexibility in thin filament-mediated contractile regulation and myopathy
Striated muscle contraction is regulated by the translocation of troponin-tropomyosin strands over the thin filament surface. Relaxation relies partly on highly-favorable, conformation-dependent electrostatic contacts between actin and tropomyosin, which position tropomyosin such that it impedes act...
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| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7229152/ https://ncbi.nlm.nih.gov/pubmed/32415060 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-15922-5 |
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