Inhibition of IRF5 cellular activity with cell-penetrating peptides that target homodimerization

The transcription factor interferon regulatory factor 5 (IRF5) plays essential roles in pathogen-induced immunity downstream of Toll-, nucleotide-binding oligomerization domain–, and retinoic acid–inducible gene I–like receptors and is an autoimmune susceptibility gene. Normally, inactive in the cyt...

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書誌詳細
出版年:Sci Adv
主要な著者: Banga, Jaspreet, Srinivasan, Dinesh, Sun, Chia-Chi, Thompson, Cherrie D., Milletti, Francesca, Huang, Kuo-Sen, Hamilton, Shannon, Song, Su, Hoffman, Ann F., Qin, Yajuan Gu, Matta, Bharati, LaPan, Margaret, Guo, Qin, Lu, Gang, Li, Dan, Qian, Hong, Bolin, David R., Liang, Lena, Wartchow, Charles, Qiu, Jin, Downing, Michelle, Narula, Satwant, Fotouhi, Nader, DeMartino, Julie A., Tan, Seng-Lai, Chen, Gang, Barnes, Betsy J.
フォーマット: Artigo
言語:Inglês
出版事項: American Association for the Advancement of Science 2020
主題:
Research Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7228753/
https://ncbi.nlm.nih.gov/pubmed/32440537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay1057
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